Cytokine Immunotherapy for Neuroblastoma

Neuroblastoma (NB) is an embryonal tumor originating from the sympathetic nervous system, which occurs during fetal period or early postnatal period, and one of most common extracranial solid malignant tumors in children. Cytokines are pleiotropic proteins that can effectively activate immune cells counteract suppression, thereby suppressing tumors. Cytokine immunotherapy provides more possibilities for application through its own induction activation system has also been extensively studied NB immunotherapy. This article mainly introduces research progress several immunotherapies based on cytokines treatment children with NB.